Insecticide resistance and the discovery of chemical and non-chemical targets for development of novel larvicides, insecticides, and repellents.Vector immunity and its effect on pathogen development.Vector microbiome and its effect on the vector and pathogens within the vector.Vector-vertebrate host interactions and how vector-derived factors affect the bite site, skin immunity, and conditions that favor pathogen transmission and pathogenesis.Pathogen-vector interactions and factors affecting pathogen development and blood feeding, and the effect of vector saliva on the transmission of vector-borne microbes.
Transgenic approaches, including genome editing tools such as CRISPR-Cas9.Population biology, genetics, genomics, and proteomics.Vector physiology and biochemical mechanisms.Ecology, epidemiology, and behavior of vectors.NIAID conducts and supports a broad range of basic research in vector biology, including projects on: Basic research conducted and supported by NIAID examines the relationship of arthropod vectors with their environment, the pathogens they transmit, and the vertebrate hosts they feed on. By understanding the mechanisms involved in these interactions, researchers can identify potential targets to impact vector populations and prevent vectors from blood feeding and transmitting pathogens.
